Resveratrol Pet Supplements: What is Resveratrol?
Resveratrol is a natural phenol most commonly found in the skin of red grapes. It can also be produced by chemical synthesis. Resveratrol was discovered by a Japanese scientist named Michio Takaoka, who isolated the phenol from the roots of the white hellborne plant. It is a poly-phenolic compound naturally found in common foods such as purple grape juice, red wine, grapes, peanuts, and some berries. Resveratrol has been shown to inhibit the growth of cancer cells and increase the lifespan in animal studies.
Resveratrol Pet Supplements: The Benefits
Resveratrol pet supplements can improve your pet’s quality of life. Studies have shown that resveratrol promotes longevity by protecting animals from age related diseases. Numerous animal studies have proven that resveratrol extends the lifespan of living organisms and slows the onset of cardiovascular and neurological age related diseases. It is also a powerful antioxidant and is being studied as a cancer preventative.
According to the Linus Pauling Institute at Oregon State University, scientific studies have shown resveratrol to have the following effects:
- Direct Antioxidant Activity
- Estrogenic and Anti-estrogenic Activities
- Biological Activities Related to Cancer Prevention
- Effects on Biotransformation Enzymes
- Preservation of Normal Cell Cycle Regulation
- Inhibition of Proliferation and Induction of Apoptosis
- Inhibition of Tumor Invasion and Angiogenesis
- Anti-inflammatory Effects
- Biological Activities Related to Cardiovascular Disease Prevention
- Inhibition of Vascular Cells
- Inhibition of Vascular Cell Adhesion Molecule Expression
- Inhibition of Smooth Muscle Cell Proliferation
- Stimulation of Endothelial Nitric Oxide Synthase (eNOS) Activity
- Inhibition of Platelet Aggregation
Resveratrol Pet Supplements: Adverse Effects of Resveratrol
Resveratrol has not been shown to be toxic or have adverse effects. According to the Linus Pauling Institute at Oregon State University, a study on rats showed that a daily oral dose of trans-resveratrol at doses up to 300mg/kg of body weight for four weeks resulted in no apparent effects.
Resveratrol Pet Supplements: Drug Interactions with Resveratrol
Studies show that resveratrol can inhibit platelet aggregation. Therefore, high intakes of resveratrol could increase bleeding risks when taken with anticoagulant drugs and NSAIDs. Resveratrol has also shown to inhibit cytochrome P450 3A4 which could possibly increase the toxicity of drugs such as calcium channel antagonists, anti-arrhythmic agents, HIV protease inhibitors, immunosuppressants, antihistamines, benzodiazepines, and drugs used to treat erectile dysfunction.
Scientific Studies on Resveratrol