Resveratrol Pet Supplements

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Resveratrol Pet Supplements: What is Resveratrol?

A Japanese scientist named Michio Takaoka was the first to discover resveratrol.

Resveratrol is a natural phenol found in common foods like:

  • purple grape juice
  • red wine
  • grapes
  • peanuts
  • some berries
  • some other plants

However, another way to produce resveratrol is by chemical synthesis.

Dr. Takaoka isolated the phenol from the roots of the white hellebore plant.

Resveratrol Pet Supplements: The Benefits

Using resveratrol pet supplements can improve your pet’s quality of life.

Studies have shown that resveratrol promotes longevity by protecting animals from age-related diseases.

Numerous animal studies have proven that resveratrol:

  • extends the lifespan of living organisms
  • slows the onset of cardiovascular and neurological age-related diseases.

It is also a powerful antioxidant and is being studied as a cancer preventative.

The Linus Pauling Institute at Oregon State University has done much research on resveratrol.

In fact, scientific studies show resveratrol has:

  • direct antioxidant activity
  • estrogenic and anti-estrogenic activities
  • biological activities related to cancer prevention
  • effects on biotransformation enzymes
  • preservation of normal cell regulation
  • inhibition of proliferation and induction of apoptosis
  • inhibition of tumor invasion and angiogenesis
  • anti-inflammatory effects
  • biological activities related to cardiovascular disease prevention
  • vascular cell inhibition
  • inhibition of vascular cell adhesion molecule expression
  • inhibition of smooth muscle cell proliferation
  • stimulation of endothelial Nitric Oxide Synthase (eNOS) activity
  • inhibition of platelet aggregation

Watch a Video on the Benefits of Resveratrol

Resveratrol Pet Supplements: Adverse Effects of Resveratrol

Research shows resveratrol as non-toxic without adverse effects.

In fact, according to the Linus Pauling Institute at Oregon State University, a study on rats showed that a daily oral dose of trans-resveratrol at doses up to 300mg/kg of body weight for four weeks resulted in no apparent effects.

Resveratrol Pet Supplements: Drug Interactions with Resveratrol

Studies show that resveratrol can inhibit platelet aggregation.

Therefore, high intakes of resveratrol could increase bleeding risks when used with anticoagulant drugs and NSAIDs.

Resveratrol has also shown to inhibit cytochrome P450 3A4,  which could possibly increase the toxicity of drugs such as:

  • calcium channel antagonists
  • anti-arrhythmic agents
  • HIV protease inhibitors
  • immunosuppressants
  • antihistamines
  • benzodiazepines
  • drugs used to treat erectile dysfunction.

Scientific Studies on Resveratrol

Combined treatment with capsaicin and resveratrol enhances neuroprotection against glutamate-induced toxicity in mouse cerebral cortical neurons.

Resveratrol improves insulin signaling in a tissue-specific manner under insulin-resistant conditions only: in vitro and in vivo experiments in rodents

Resveratrol Inhibits IL-1β–Induced Stimulation of Caspase-3 and Cleavage of PARP in Human Articular Chondrocytes in Vitro

Effects of dietary resveratrol supplementation on egg production and antioxidant status.

Resveratrol protects quail hepatocytes against heat stress: modulation of the Nrf2 transcription factor and heat shock proteins.

Resveratrol-Induced Apoptosis Is Mediated by Early Growth Response-1, Krüppel-Like Factor 4, and Activating Transcription Factor 3

Effects of dietary resveratrol supplementation on egg production and antioxidant status.


The growth of the canine glioblastoma cell line D-GBM and the canine histiocytic sarcoma cell line DH82 is inhibited by the resveratrol oligomers opeaphenol and r2-viniferin

Two New Research Projects Study Resveratrol’s Effects on EMS



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